Stability of amphotericin B in infusion bottles.

نویسندگان

  • E R Block
  • J E Bennett
چکیده

Intravenous solutions of amphotericin B in 5% dextrose water with or without hydrocortisone or heparin demonstrated no appreciable loss of activity when exposed to fluorescent light for up to 24 h at 25 C (room temperature).

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OBJECTIVE To test the hypothesis that amphotericin B deoxycholate is less toxic when given by continuous infusion than by conventional rapid infusion. DESIGN Randomised, controlled, non-blinded, single centre study. SETTING University hospital providing tertiary clinical care. PATIENTS 80 mostly neutropenic patients with refractory fever and suspected or proved invasive fungal infections....

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 4 6  شماره 

صفحات  -

تاریخ انتشار 1973